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PANDEMIC PREPAREDNESS FOR BUSINESSES
PANDEMIC PREPAREDNESS FOR BUSINESSES
PANDEMIC FLU
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PANDEMIC FLU
More interested in Bird Flu specifically? See our FAQ on Bird Flu Information .
Q. What is pandemic flu?
Flu that spreads rapidly causing
widespread epidemics around the world. Pandemic
flu occurs when a new, highly infectious and dangerous strain of the
flu virus appears.
In contrast to the 'ordinary' or 'seasonal', flu outbreaks
which we see every winter, flu pandemics occur infrequently - usually every few
decades. There were three in the last century. The most serious was in 1918, killing
millions of people worldwide. Smaller pandemics happened in 1957 and 1968.
Q. What is the difference between an epidemic and a pandemic?
A pandemic occurs over large geographical areas (usually
worldwide) and affects a high proportion of the population; an epidemic,
although it may be serious, usually refers to what is happening in one country
or region.
Q. Is another pandemic of flu likely?
Flu viruses are constantly changing and adapting, so it is
likely that viruses sufficiently different from 'ordinary' flu strains to cause
a pandemic will emerge from time to time. International disease experts are
saying that the world is overdue for the next pandemic.
Q. When is the next pandemic due?
We do not know - it can't be predicted. The gaps between
previous pandemics have varied widely. Intervals between previous pandemics
have varied from 11 to 42 years with no recognisable pattern. Three flu
pandemics occurred in the last century - 1918/19 (Spanish flu), 1957/58 (Asian
flu) and 1968/69 (Hong Kong flu). All affected large numbers of the population, causing many deaths and huge economic and
social disruption.
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PANDEMICS DURING THE LAST CENTURY
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Years
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1918-1919 |
1957-1958 |
1968-1969 |
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Flu
type
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Spanish Flu |
Asian Flu |
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Likely
origin |
Unknown (The first cases were in Europe and |
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|
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Estimated
deaths Worldwide
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50Million |
1 Million |
1 Million |
Q. Where is the new virus likely to come from?
Past experience suggests that it will first appear in Asia, but it could be anywhere.
Q. Will it arrive in winter like normal flu?
Not necessarily. A new virus may not follow the usual
seasonal pattern of ordinary flu. It could occur at any time of the year.
Q. How long will it take to spread around the world?
Q. How is the virus spread? Q. How will a new virus be detected? Q. How will we know when a pandemic is possible? Q. Can't it be prevented at this stage? Q. What will make a pandemic more likely to happen? Q. What can we expect to happen? Q. How many people are likely to catch flu during the pandemic? Q. Could everyone become ill? Q. How predictable will the effects of a pandemic be? Q. How will this impact on health services? Q. How will this impact on business? Q. Will schools be affected? Q. Will other sectors of the community be affected? Q. Will people be prevented from travelling? Q. Will the health services be able to cope with so many patients all at
once? Q. Who is at risk? Q. What are the differences between pandemic flu and ordinary
flu? Pandemic flu is caused by a new or novel strain of flu
virus. One way that this could happen is as a result of an avian flu virus and
ordinary flu virus mixing their genes to produce a "human bird flu" virus that can spread
between people. Because it is new, no one has any protection against it and
until it is identified, a vaccine cannot be developed against it. It can
therefore spread very rapidly and cause high rates of illness and death. See
the table on page 7 for a summary of many of the differences between ordinary
and pandemic flu. Q. How many people are likely to die? Q. How long will the pandemic last?
Probably less than six months and
possibly just a few weeks. The increasing speed and volume of modern travel means infectious diseases can travel very rapidly round
the globe.
The virus is easily passed from person to person by
breathing in air containing the virus produced when an infected person talks,
coughs or sneezes. It can also spread through hand/face contact after touching
a person or surface contaminated with the virus.
Scientists in an international network of laboratories,
co-ordinated by the World Health Organization (WHO) are watching for it all the
time. This network provides a mechanism for monitoring flu viruses and avian flu information around the
world, detecting the emergence of flu viruses with pandemic potential,
and alerting other countries.
When a new strain of flu virus has not only been
identified but also causing illness and has started spreading from one person to another.
International effort will be put to trying to control a
pandemic at this early stage. However, flu is highly infectious and
because whole populations will be susceptible to the new virus, despite
people's best efforts it is likely to continue to spread.
A pandemic will be considered imminent when a new virus has
shown it can spread easily between people. In practice, this means when a new
strain of the virus has been identified as the cause of chains of illness
passed from one person to another or illness in more than one country, with no
obvious links.
Once the pandemic reaches your Country it will take a few
weeks to take hold, but it will then cause widespread illness across the
country over a period of 2-3 months. There may be a second wave of illness a
few weeks or months later. Previous experience suggests around a quarter of the
population will develop flu during this time.
From past experience, up to a quarter of the population are
likely to develop flu, although it could be more. More than this may be
infected without getting symptoms (sub-clinical infection).
Everyone will be susceptible, but in the past as many people
as become ill shake off the infection without developing illness (asymptomatic
infection).
Every pandemic is different so we cannot be sure how a new
pandemic will behave. But we can make sensible plans for what we think is most likely, based on previous
experience and our knowledge of how the world has changes since the last
pandemic in 1968.
A flu pandemic will, therefore, place considerable pressure
on health and social services due to the greatly increased number of patients
with flu who will require treatment together with depletion of the
workforce due to illness.
Each pandemic is different and the impact on business cannot
be fully established until more is known about how a pandemic is evolving.
Absences from work will depend largely on the age group most affected by the
virus. Previous pandemics suggest that up to 10% or more of the population may
have to take days of work. Absence may be compounded by the need for some
workers to care for family members, and any disruption to transport services.
Pandemic flu is likely to spread rapidly in schools, so they
may have to close. Some may also have to close for short periods because of staff
shortages. This, in turn, will affect working parents who may need to stay at
home to care for their children. Closing schools will, therefore, have an
impact on business continuity and the maintenance of essential services.
Decisions such as whether to close schools as a measure to try to slow the
spread of the pandemic will be taken at the time.
Pandemic flu will impact on al services including health,
police, fire, the military, fuel supply, food preparation, distribution and
transport, prisons, education and business. Al are likely to be affected by
staff sickness, travel restrictions and other potentially restrictive
countermeasures, and by the knock-on effects of reduced transport, deliveries
etc.
At the start of a pandemic people are likely to be advised not
to travel to affected areas or attend international gatherings such as large conferences
and sports events. Later, depending on how the disease develops, measures may
have to be taken to restrict people's movements to prevent or delay further
spread of the disease.
There will certainly be greatly increased pressure on the
health services, which is used to planning for such emergencies. A flu pandemic
is one of the more serious crises which the health services plan for.
Everyone is at risk during a flu pandemic, as no one will
have immunity to the virus. Older people and those with chronic health problems
may be at greater risk of severe complication like pneumonia but until the
virus starts circulating it is not possible to know for sure who is at greatest
risk.
Ordinary flu is the flu that circulates in the human
population al the time and produces the winter flu we see every year. Ordinary
flu viruses are monitored closely. The strains likely to be circulating each year can be fairly reliably
predicted so that appropriate vaccines can be prepared each year.
This will depend on factors such as how virulent the virus
proves to be, which age groups are mainly affected, and how much vaccine is
available. According to recent estimates, 25% of the population could fall ill.
It is estimated that a pandemic could lead to several million deaths worldwide.
It is estimated that pandemic flu will be widespread within
about ten weeks of its first arriving in a Country, and will last for about
three months. There may be a second wave of infection a few months later. These
times are estimates, and may change.
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06/25/2009 05:00 PM
Preclinical Proof-of-Concept Studies Published For Novavax Seasonal Influenza Virus-Like-Particle Vaccine
Novavax, Inc. (Nasdaq: NVAX) announced publication of the preclinical study results that supported the clinical development of the company's investigational VLP vaccine against the H3N2, H1N1 and B influenza strains. The study, which was conducted by scientists from the University of Pittsburgh, Center for Vaccine Research and Novavax, was published in the June 24, 2009 online issue of PLoS ONE.
06/05/2009 08:00 PM
A Closer Look At The I-Con™ - Isolation And Containment For Pandemic Control
American Innovative Research (A.I.R.) cofounders, David Palmer and Judy Piscione, explain how the impact of the avian flu pandemic originally motivated their company's researching a home option of an isolation and containment unit. A.I.R. CEO Palmer states that he and Piscione leveraged decades of success in biomedical research and semiconductor clean-room technology to found American Innovative Research Corp. Palmer defines A.I.R.
06/05/2009 06:00 PM
Animal Production And Health To Be Addressed At FAO/IAEA Symposium
An international symposium to be held in Vienna next week will focus on the use of nuclear technologies to enhance animal nutrition and reproduction strategies and to detect and control animal-origin diseases that can be transmitted to humans, such as swine and avian influenza. Around 500 animal production and health experts from over 100 countries will present up-to-date findings for solving or alleviating factors affecting animal production.
06/04/2009 04:00 PM
Indirect Transmission Can Trigger Influenza Outbreaks In Birds
New data on the persistence of avian influenza viruses in the environment has allowed a team of University of Georgia researchers to create the first model that takes into account both direct and indirect transmission of the viruses among birds. The model, which is detailed in the early online edition of the journal Proceedings of the National Academy of Sciences, has the potential to shed new light on how outbreaks begin in wild bird populations.
06/02/2009 06:00 PM
News From The American Chemical Society, May 27, 2009
Bird flu virus remains infectious up to 600 days in municipal landfills Amid concerns about a pandemic of swine flu, researchers from Nebraska report for the first time that poultry carcasses infected with another threat - the "bird flu" virus - can remain infectious in municipal landfills for almost 2 years. Their report is scheduled for the June 15 issue of ACS' semi-monthly journal Environmental Science & Technology. Shannon L.
05/31/2009 04:00 PM
Bird Flu Virus Remains Infectious Up To 600 Days In Municipal Landfills
Amid concerns about a pandemic of swine flu, researchers from Nebraska report for the first time that poultry carcasses infected with another threat - the "bird flu" virus - can remain infectious in municipal landfills for almost 2 years. Their report is scheduled for the June 15 issue of ACS' semi-monthly journal Environmental Science & Technology. Shannon L.
05/25/2009 04:00 PM
The Challenges Of Avian Influenza Virus: Mechanism, Epidemiology And Control
The latest special issue of Science in China Series C: Life Sciences focuses on the recent progress in the H5N1-related research field. Early 2009, eight human infection cases of H5N1 highly pathogenic avian influenza (HPAI) virus, with 5 death cases, were reported in China. This again made the world alert on a possible pandemic worldwide, probably caused by avian-origin influenza virus.
05/25/2009 03:00 PM
Tighter Surveillance Of Swine Flu In Pigs Needed Worldwide Says CDC
The US Centers for Disease Control and Prevention (CDC) said that there is a "global need for more systemic surveillance of influenza viruses in pigs", during a press briefing where they explained the findings of a recent study on the genetic and antigenetic properties of the new 2009 H1N1 swine flu virus.
05/20/2009 10:00 PM
In A New Way Of Treating The Flu, Both The H And N Portions Of The Virus Are Targeted
What happens if the next big influenza mutation proves resistant to the available anti-viral drugs? This question is presenting itself right now to scientists and health officials this week at the World Health Assembly in Geneva, Switzerland, as they continue to do battle with H1N1, the so-called swine flu, and prepare for the next iteration of the ever-changing flu virus.
05/19/2009 09:00 PM
New Vaccine Strategy Might Offer Protection Against Pandemic Influenza Strains
A novel vaccine strategy using virus-like particles (VLPs) could provide stronger and longer-lasting influenza vaccines with a significantly shorter development and production time than current ones, allowing public health authorities to react more quickly in the event of a potential pandemic. Ted Ross, Ph.D.
05/13/2009 08:00 PM
News From Burnham Institute For Medical Research, May 2009
Human monoclonal antibodies effective against bird and seasonal flu viruses Dr. Robert Liddington and colleagues, working with researchers at the Dana-Farber Cancer Institute and the Centers for Disease Control and Prevention, reported the identification of human monoclonal antibodies that neutralize an unprecedented range of influenza A viruses, including avian influenza A (H5N1) virus, previous pandemic influenza viruses and some seasonal influenza viruses.
05/11/2009 06:00 PM
Bird Flu Research Could Help With Swine Flu Vaccine
A study published this week in the Proceedings of the National Academy of Sciences of the United States of America shows that Aflunov®, the Novartis investigational pre-pandemic avian influenza vaccine formulated with Novartis' proprietary MF59® adjuvant, can elicit a broadly cross-reactive immune response covering all known H5N1 antigenic variants, even when that booster dose is administered six years after the initial priming dose.
05/05/2009 11:00 PM
EFPIA Response To The A (H1N1) Novel Influenza Virus
EFPIA is aware and concerned by the current outbreak of a novel influenza, which appears to have originated in Mexico. We note the WHO's decision to raise the level of influenza pandemic alert from the current phase 4 to phase 5. We will continue to monitor the situation closely, working with our colleagues at the International Federation of Pharmaceutical manufacturers and Associations.
05/02/2009 07:00 PM
Novartis Investigational Adjuvanted (MF59) Pre-pandemic Avian Influenza Vaccine Aflunov® Shows Long Lasting, cross-protective Immune Response
A study published this week in the Proceedings of the National Academy of Sciences of the United States of America shows that Aflunov®, the Novartis investigational pre-pandemic avian influenza vaccine formulated with Novartis' proprietary MF59® adjuvant, can elicit a broadly cross-reactive immune response covering all known H5N1 antigenic variants, even when that booster dose is administered six years after the initial priming dose.
04/30/2009 06:00 PM
Avian Flu Research Sheds Light On Swine Flu Outbreak
A new study by University of Maryland researchers suggests that the potential for an avian influenza virus to cause a human flu pandemic is greater than previously thought. Results also illustrate how the current swine flu outbreak likely came about. As of now, avian flu viruses can infect humans who have contact with birds, but these viruses tend not to transmit easily between humans.
04/29/2009 03:00 PM
Is Swine Flu A Worldwide Threat?
After human cases of a new H1N1 swine influenza A virus were first reported in Mexico and then quickly spread around the world, the World Health Organization (WHO) raised its pandemic alert level from phase 3 to phase 4, on April 27. The virus is a fusion of human, pig and avian influenza. There was growing international concern a week ago, after outbreaks of illnesses similar to influenza were reported in Mexico and in other countries.
04/29/2009 03:00 PM
Swine Flu Baffles Experts And Raises More Questions Than Answers
As countries around the world ready themselves for the possibility of a global pandemic in the wake of increasing numbers of confirmed cases of people infected with a new strain of A/H1N1 influenza virus that is being described as swine flu, investigations digging deeper into the history and evidence surrounding the outbreak are coming up with more questions than answers.
04/28/2009 11:00 PM
NanoViricides, Inc. Says Flu-Cide Drug Designed To Destroy All Influenza A Viruses Including Swine And Bird Flu
NanoViricides, Inc. (OTC BB: NNVC.OB) (the "Company"), announced that it is developing FluCide(™), its flagship anti-influenza drug candidate, to work against all influenza types and subtypes. FluCide has been shown to be effective against both common influenza subtype H1N1, as well as two different variants of bird flu subtype H5N1.
04/28/2009 09:00 PM
Pandemic Flu Vaccine 6-Month Time Lag Warns Scientist
New research published April 27 from the University of Leicester and University Hospitals of Leicester NHS Trust warns of a six-month time lag before effective vaccines can be manufactured in the event of a pandemic flu outbreak. By that time, the first wave of pandemic flu may be over before people are vaccinated, says Dr Iain Stephenson, Consultant in Infectious Diseases at the Leicester Royal Infirmary and a Clinical Senior Lecturer at the University of Leicester.
04/28/2009 06:00 PM
Scientist Warns Over Pandemic Flu Vaccine Six-month Time Lag
New research published from the University of Leicester and University Hospitals of Leicester NHS Trust warns of a six-month time lag before effective vaccines can be manufactured in the event of a pandemic flu outbreak. By that time, the first wave of pandemic flu may be over before people are vaccinated, says Dr Iain Stephenson, Consultant in Infectious Diseases at the Leicester Royal Infirmary and a Clinical Senior Lecturer at the University of Leicester.








